Acyl-Coenzyme A: cholesterol acyltransferase-2 -ACAT-2) catalyzes the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A. It is associated with lipoprotein particle secretion and thus plays an important role in the metabolism of triglyceride-rich lipoproteins like ApoB100. In humans, ACAT-2 is primarily expressed in the small intestine, whereas in other mammals, the enzyme is expressed in the liver and the small intestine. Human ACAT-2 has 522 amino acid with an estimated molecular weight of 60 kDa. Cayman s antibody detects ACAT-2 at about 60 kDa in mouse liver, intestine, and fibroblasts.
應(yīng)用類型
WB, ICC, and IHC
免疫原
human ACAT-2 amino acids 3-20 -PGGARLRLQRTEGLGGER)
來源宿主
rabbit
反應(yīng)性
Human ACAT-2+|Mouse ACAT-2+|Rat ACAT-2+|Porcine ACAT-2+|Ovine ACAT-2+