Latanoprost-d4 contains four deuterium atoms at the 3, 3 , 4, and 4 positions. It is intended for use as an internal standard for the quantification of latanoprost by GC- or LC-mass spectrometry. Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2.alpha.. It is a prodrug form of the free acid, which is a potent agonist of the FP receptor in the eye. Latanoprost reduces intraocular pressure in glaucoma patients with few side effects. The EC50 value of latanoprost for -free acid) for FP receptors is 3.6 nM.
產(chǎn)品描述
An internal standard for the quantification of Latanoprost by GC- or LC-MS.