Anandamide -AEA) is a substrate for cyclooxygenase and the conversion of this fatty acid amide to PGE2 compounds has been demonstrated in vitro. Conversion into any of the other primary PGs is also theoretically possible. In addition, these compounds are intresting analogs of the parent PG and may have useful pharmacologic uses. PGD2-EA is one of these analogs.
產(chǎn)品描述
PGD2-EA is produced when LPS-stimulated macrophages expressing COX-2 are exposed to the substrate AEA.{11045} The physiological function of PGD2-EA has not been determined.