Acridinium esters can replace radioactive isotopes in numerous applications -e.g., immunoassays, antibody labeling, etc.). Their sensitivity is comparable to radiolabeled reagents without the disposal issues associated with radioactive waste. 10-methyl-9--phenoxycarbonyl) Acridinium fluorosulfonate -PMAC) is a sensitive tool for detection of reactive oxygen species -ROS). When immobilized onto polymer microspheres, it can be phagocytized by cells and used as an internal ROS detector. The chemiluminescence of PMAC can be initiated using hypoxanthine/xanthine oxidase or hydrogen peroxide at physiological pH.
產(chǎn)品描述
A sensitive tool for detection of reactive oxygen species -ROS); can be phagocytized by cells and used as an internal ROS detector when immobilized onto polymer microspheres; hypoxanthine/xanthine oxidase or hydrogen peroxide at physiological pH initiates chemiluminescence