- 中文名稱
9-Z),11-E),13-E)-Octadecatrienoic Acid (50 mg)
- 英文名字
- 供應(yīng)商
- Cayman
- 產(chǎn)品貨號
- 10008349-50
- 產(chǎn)品報(bào)價(jià)
- ￥7840/50 mg
- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購買方式
- 產(chǎn)品新聞
- 背景資料
- 9-Z),11-E),13-E)-Octadecatrienoic Acid -.alpha.-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. .alpha.-ESA is metabolized and converted to conjugated linoleic acid -9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, .alpha.-ESA induced apoptosis through up-regulation of GADD45, p53, and PPAR.gamma.. In DLD-1 cells supplemented with .alpha.-ESA, apoptosis was induced via lipid peroxidation with an EC50 of 20 uM. It also inhibits DNA polymerases and topoisomerases with IC50s ranging from ~5-20 uM for different isoforms of the enzymes.
- 產(chǎn)品描述
- .alpha.-ESA is a conjugated PUFA commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil.{14176} .alpha.-ESA is metabolized and converted to conjugated linoleic acid -9Z,11E-CLA) in rats.{14175} It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, .alpha.-ESA induced apoptosis through up-regulation of GADD45, p53, and PPAR.gamma..{14176} In DLD-1 cells supplemented with .alpha.-ESA, apoptosis was induced via lipid peroxidation with an EC50 of 20 uM.{14175} It also inhibits DNA polymerases and topoisomerases with IC50s ranging from ~5-20 uM for different isoforms of the enzymes.{14174}
- 產(chǎn)品形式
- 保存建議
- -80
- 其他
- Cayman Chemical
- 注意
-
該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前，請瀏覽說明書確認(rèn)。
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