D-myo-Inositol-1,2,5,6-tetraphosphate -Ins-1,2,5,6)P4) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals.. Ins-1,2,5,6)P4 binds to the murine Grp-1 PH domain with a Kd-apparent) of 0.18 uM, which is about 6.7-fold higher than for Ins-1,3,4,5)P4. It binds to rat heart membranes and significantly decreases heart rate in a pithed rat model.
產(chǎn)品描述
Ins-1,2,5,6)P4 is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals.{8672,8344,13727}. Ins-1,2,5,6)P4 binds to the murine Grp-1 PH domain with a Kd-apparent) of 0.18 uM, which is about 6.7-fold higher than for Ins-1,3,4,5)P4.{13724} It binds to rat heart membranes and significantly decreases heart rate in a pithed rat model.{14740}