D-myo-Inositol-1,2,3,4-tetraphosphate -Ins-1,2,3,4)-P4) is one of the many inositol phosphate -InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals. Ins-1,2,3,4)-P4 exhibits agonist activity at the Ins-1,4,5)-P3 receptor expressed in CHO cells where it induces Ca2+ mobilization with an ED50 value of 18.1 uM, making it nearly 180-fold less effective than Ins-1,4,5)-P3 in the same assay.
產(chǎn)品描述
Ins-1,2,3,4)-P4 is one of the many InsP isomers that could act as small, soluble second messengers in the transmission of cellular signals.{8672,8344,13727} Ins-1,2,3,4)-P4 exhibits agonist activity at the Ins-1,4,5)-P3 receptor expressed in CHO cells where it induces Ca2+ mobilization with an ED50 value of 18.1 uM, making it nearly 180-fold less effective than Ins-1,4,5)-P3 in the same assay.{5630}