D-myo-Inositol-1,2,4,5-tetraphosphate -Ins-1,2,4,5)P4) is one of the many inositol phosphate -InsP) isomers that act as small, soluble second messengers in the transmission of cellular signals.. Ins-1,2,4,5)P4 exhibits agonist activity at the Ins-1,4,5)P3 receptor expressed in CHO cells where it induces Ca2+ mobilization with an ED50 value of 0.22 uM, making it nearly equipotent to Ins-1,4,5)P3 -EC50 = 0.1 uM) in the same assay.
產(chǎn)品描述
D-myo-Inositol-1,2,4,5-tetraphosphate -Ins-1,2,4,5)P4) is one of the many inositol phosphate -InsP) isomers that act as small, soluble second messengers in the transmission of cellular signals.{8672,8344,13727}. Ins-1,2,4,5)P4 exhibits agonist activity at the Ins-1,4,5)P3 receptor expressed in CHO cells where it induces Ca2+ mobilization with an ED50 value of 0.22 uM, making it nearly equipotent to Ins-1,4,5)P3 -EC50 = 0.1 uM) in the same assay.{5630}