D-myo-Inositol-2,3,4,5-tetraphosphate -Ins-2,3,4,5)-P4) is a member of the inositol phosphate -InsP) family of molecules that play a critical role as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins-1,4,5)-P3, more commonly referred to as IP3, is a second messenger produced in cells by phospholipase C -PLC)-mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. Binding of Ins-1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium.
產(chǎn)品描述
D-myo-Inositol-2,3,4,5-tetraphosphate -Ins-2,3,4,5)-P4) is a member of the inositol phosphate -InsP) family of molecules that play a critical role as small, soluble second messengers in the transmission of cellular signals.{8672,8344} The most studied InsP, Ins-1,4,5)-P3, more commonly referred to as IP3, is a second messenger produced in cells by phospholipase C -PLC)-mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate.{2429,5714} Binding of Ins-1,4,5)-P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium.{5714,4096}