The enzyme fatty acyl amide hydrolase -FAAH) is widely expressed in brain and other tissues, and is capable of hydrolyzing anandamide -AEA) and other simple esters and amides with long unsaturated acyl chains. JP83 is an irreversible FAAH inhibitor of the carbamate class with an IC50 of 14 nM for the human recombinant enzyme when tested using radiolabeled oleamide as the substrate.
產(chǎn)品描述
An irreversible FAAH inhibitor of the carbamate class with an IC50 value of 14 nM for the human recombinant enzyme when tested using radiolabeled oleamide as the substrate