中文名稱

N-Palmitoyl Glycine (1 mg)

英文名字

N-Hexadecanoyl-Glycine|PalGly, N-Palmitoyl Glycine, N-(1-oxohexadecyl)-glycine

供應商

Cayman

產(chǎn)品貨號

10009020-1

產(chǎn)品報價

￥182/1 mg

產(chǎn)品說明書

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產(chǎn)品新聞

背景資料

The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolamide -AEA; anandamide). N-palmitoyl glycine -PalGly) contains an 18-carbon saturated fatty acid that is amide-linked to glycine and is structurally similar to the phospholipid-derived N-acyl ethanolamines. Endogenously produced in rat skin and spinal cord, PalGly is present in 100-fold greater amounts in skin and 3-fold greater in brain compared to AEA. Injection of 0.43 ug PalGly in rat hindpaw inhibits heat-induced firing of nociceptive neurons in rat dorsal horn. PalGly treatment induces transient calcium influx in native dorsal root ganglion -DRG) cells and in the PTX-sensitive, DRG-like cell line F-11 -EC50 = 5.5 uM).

產(chǎn)品描述

an 18-carbon saturated fatty acid that is structurally similar to the phospholipid-derived N-acyl ethanolamines; inhibits heat-induced firing of nociceptive neurons in rat dorsal horn; induces transient calcium influx in native dorsal root ganglion -DRG) cells and in the PTX-sensitive, DRG-like cell line F-11 -EC50 = 5.5 uM)

產(chǎn)品形式

保存建議

-20

其他

Cayman Chemical

注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準確的產(chǎn)品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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