中文名稱

PtdIns-(4)-P1結合蛋白 (100 ug)

英文名字

PtdIns-(4)-P1 Binding Protein (100 ug)

供應商

Cayman

產(chǎn)品貨號

10009241-100

產(chǎn)品報價

￥4634/100 ug

產(chǎn)品說明書

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背景資料

Pleckstrin homology -PH) domains all contain a seven-standard .beta.-sandwich that allows binding to various species of phosphatidyl inositol -PtdIns) phosphates. Most PH domains bind to phosphatidylinositol phosphates -PIPs) with weak affinity and low specificity, however, a small subclass does bind specifically and with high-affinity for certain PIPs. PtdIns--4)-P1 Binding Protein contains a highly specific PH domain that recognizes and binds PtdIns--4)-P1. PIPs represent a small percentage of total membrane phospholipids however, they play a critical role in the generation and transmission of cellular signals. PtdIns--4)-P1 can phosphorylated by kinases to give bi- and triphosphates such as PtdIns--4,5)-P2 and PtdIns--3,4,5)-P3. Phosphorylation of PtdIns--4)-P1 by phosphoinositide -PI)3-kinase to make PtdIns--3,4)-P2 initiates an intricate signalling cascade that has been implicated in cancer.

序列

來源宿主

溶解建議

保存建議

-80

其他

Cayman Chemical

注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準確的產(chǎn)品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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