中文名稱

1-Stearoyl-2-Arachidonoyl-sn-Glycerol-d8 (5 mg)

英文名字

SAG-d8, 1-Stearoyl-2-Arachidonoyl-sn-Glycerol-d8, 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-5,6,8,9,11,12,14,15-d8-sn-glycerol

供應(yīng)商

Cayman

產(chǎn)品貨號

10009872-5

產(chǎn)品報價

￥21070/5 mg

產(chǎn)品說明書

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產(chǎn)品新聞

背景資料

SAG-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of SAG by GC- or LC-mass spectrometry. Many protein kinase C -PKC) isoforms require activation via second messengers including Ca2+, diacylglycerol -DAG), and/or a phospholipid in order to phosphorylate target proteins, initiating a variety of important signaling cascades. 1-Stearoyl-2-arachidonoyl-sn-glycerol -SAG) is a DAG that contains the .omega.-6 polyunsaturated fatty acid arachidonic acid in the sn-2 position and stearic acid in the sn-1 position of the glycerol backbone. It can potently activate PKC.alpha., .epsilon., and .delta. at nM concentrations. Independent of PKC signaling, SAG competitively binds to the Ras activator RasGRP with a Ki value of 4.49 uM in Jurkat T-cells.

產(chǎn)品描述

An internal standard for the quantification of SAG by GC- or LC-MS

產(chǎn)品形式

保存建議

-20

其他

Cayman Chemical

注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準確的產(chǎn)品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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