Misoprostol is a widely sold analog of prostaglandin E1 -PGE1) which has potent but relatively non-selective agonist activity with respect to the prostanoid EP receptor subgroup. Misoprostol has been used therapeutically for many years in humans for the treatment of gastric ulcer disease under the Searle tradename Cytotec. 8-iso Misoprostol is one of several impurities which are possible in the production of bulk commercial preparations of misoprostol, and is somewhat difficult to distinguish from other impurities such as 11.beta.-misoprostol. The pharmacology and EP receptor binding affinity for 8-iso misoprostol has not been published.
產(chǎn)品描述
8-iso Misoprostol is one of several possible impurities in the production of bulk commercial preparations of misoprostol, and one that is somewhat difficult to distinguish from other impurities such as 11.beta.-misoprostol.{10909} The pharmacology and EP receptor binding affinity for 8-iso misoprostol has not been published.