- 中文名稱
Anti-Human MMP-3
- 英文名字
- Anti-Human MMP-3
- 供應商
- ReliaTech
- 產品貨號
- 101-M110
- 產品報價
- ¥詢價/100ug

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP3 (stromelysin1), can degrade a broad range of substrates including collagen α chains, aggrecan, laminin, fibronectin, elastin, casein, α1 antitrypsin, myelin basic protein, IL1β, IGFBP3, pro MMP1, pro MMP7, pro MMP8, pro MMP9 and pro MMP13. MMP3 does not cleave the triple helical region of interstitial collagens, a characteristic which distinguishes the stromelysins from the collagenases. The MMP3 substrate repertoire extends beyond extracellular matrix proteins and implicates MMP3 in roles other than direct tissue remodelling, for instance, enzyme cascades and cytokine regulation. MMP3 is expressed by fibroblasts, chrondrocytes, osteoblasts, endothelial cells, smooth muscle cells and macrophages. Structurally, MMP3 may be divided into several distinct domains? a prodomain which is cleaved upon activation? a catalytic domain containing the zinc binding site? a short hinge region and a carboxyl terminal (hemopexinlike) domain.
- 應用類型
- WB, IHC (P)
- 免疫原
- 該Anti-Human MMP-3的詳細信息查看ReliaTech提供的產品說明書。
- 來源宿主
- 該Anti-Human MMP-3的詳細信息查看ReliaTech提供的產品說明書。
- 反應性
- 該Anti-Human MMP-3的詳細信息查看ReliaTech提供的產品說明書。
- 保存建議
- 該Anti-Human MMP-3的詳細信息查看ReliaTech提供的產品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
- 其他
- ReliaTech全稱為受體配體技術有限公司 (Receptor Ligand Technologies GmbH),1999年成立,總部位于德國不倫瑞克,是一家后基因組生物技術公司。ReliaTech主要專注于受體和配體的發(fā)現與研究。此外,ReliaTech也開發(fā)應用于血管與淋巴管生成研究的相關高品質試劑。目前ReliaTech提供近2800款產品,產品線主要包括重組蛋白(細胞因子、生長因子、可溶性受體)、抗體、ELISA試劑盒等。

- 注意
-
該頁面的中文產品信息的翻譯,僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前,請瀏覽說明書確認。
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