Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP10 (stromelysin 2) degrades a broad range of substrates including gelatin, collagen types III, IV and V, fibronectin, aggrecan, and pig cartilage proteoglycan. MMP10 can activate other MMPs such as MMP1 and MMP8. MMP10 is expressed in keratinocytes, T cells, menstrual endometrium and a few tumor samples. Structurally, MMP10 may be divided into four distinct domains: a prodomain which is cleaved upon activation, a catalytic domain containing the zinc binding site? a short linker region, and a carboxyl terminal hemopexin- slike domain.
應用類型
WB, IHC (P)
免疫原
該Anti-Human MMP-10的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
來源宿主
該Anti-Human MMP-10的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
反應性
該Anti-Human MMP-10的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
保存建議
該Anti-Human MMP-10的詳細信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.