Anti-Human CART-Anti-Human CART代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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背景資料: CART, also known as cocaine and amphetaminerelated transcript, is a 10 kDa secreted polypeptide produced by neuronal cell types in a variety of locations. In human, the molecule is synthesized as a 116 amino acid (aa) precursor with a 27 aa signal sequence an 89 aa mature segment. There are six Cterminal cysteines that form three intrachain disulfide bonds, and the potential exists for both sulfation and phosphorylation in the N terminal region. There are numerous monobasic and dibasic sites for enzyme cleavage, and multiple, presumably proteolyticallygenerated short forms are known to exist. These include a 5K, 48 aa peptide (CART 42- 89), and a 4.3K, 40 aa peptide (CART 49-89). Human CART is 98% aa identical to both mouse and rat CART (189). Although CART suppresses feeding and increases pain tolerance, there would appear to be differences between the various forms of CART on other functions. In addition, anatomical location is associated with differing lengths of CART. For example, 89 aa and 79 aa forms are found in the adrenal, while 48 aa and 44 aa forms are found in the hypothalamus.

保存建議: 該Anti-Human CART的詳細(xì)信息查看ReliaTech提供的產(chǎn)品說(shuō)明書(shū)。溶解建議：Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.

其他: ReliaTech全稱為受體配體技術(shù)有限公司 (Receptor Ligand Technologies GmbH)，1999年成立，總部位于德國(guó)不倫瑞克，是一家后基因組生物技術(shù)公司。ReliaTech主要專(zhuān)注于受體和配體的發(fā)現(xiàn)與研究。此外，ReliaTech也開(kāi)發(fā)應(yīng)用于血管與淋巴管生成研究的相關(guān)高品質(zhì)試劑。目前ReliaTech提供近2800款產(chǎn)品，產(chǎn)品線主要包括重組蛋白(細(xì)胞因子、生長(zhǎng)因子、可溶性受體)、抗體、ELISA試劑盒等。

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