Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. In humans each group of receptors is encoded by 2 - 3 closely related genes designated A, B, and C. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Different Fc receptors can function as activators, as inhibitors, or as decoy receptors.
應用類型
WB, FC
免疫原
該Anti-Human CD16b的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
來源宿主
該Anti-Human CD16b的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
反應性
該Anti-Human CD16b的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
保存建議
該Anti-Human CD16b的詳細信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.