- 中文名稱
Anti-Human Follistatin like-protein 1/FSTL1
- 英文名字
- Anti-Human Follistatin like-protein 1/FSTL1
- 供應商
- ReliaTech
- 產品貨號
- 101-M422
- 產品報價
- ￥詢價/100ug
- 產品說明書
- 點擊查看
- 購買方式
- 90%產品中國有現(xiàn)貨庫存。銀行轉賬、電匯、支票、現(xiàn)金，在線支付寶及網銀支付，或直接與我們電話聯(lián)系400-6800-868
- 產品新聞
- 背景資料
- Follistatin-like 1 (FSL1 or FSTL1), also known as FRP (follistatin-related protein), Flik (follistatin-like), and TSC36 (TGFβ1stimulated clone 36), is a secreted 45-55 kDa extracellular glycoprotein belonging to the BM40/ SPARC/Osteonectin family. The human FSTL1 cDNA encodes 308 amino acids (aa), including a 20 aa signal sequence, a cysteinerich Follistatin (EGF and kazal-like) domain, two apparently non-functional EF hand calciumbinding motifs, and a von Willebrand Factor C homology domain. Mature human FSTL1 shares 94%, 95%, 98%, and 99% aa identity with mouse, rat, bovine, and equine FSTL1, respectively. FSTL1 was first identified as a TGF-beta-induced protein from a mouse osteoblast cell line (4). It is ubiquitously expressed in early mouse development, but is mainly mesenchymal later in development. In humans, FSTL1 is a common rheumatoid arthritis autoantigen. It is reported to be either proinflammatory due to promoting inflammatory cytokine secretion, or to prevent autoimmune arthritis by inhibiting matrix metalloproteinase (MMP) and prostaglandin expression. In muscle and heart, it appears to be protective and promotes endothelial cell functions such as revascularization after ischemia, probably due to promoting expression and activation of the protein kinase AKT1.
- 應用類型
- WB
- 免疫原
- 該Anti-Human Follistatin like-protein 1/FSTL1的詳細信息查看ReliaTech提供的產品說明書。
- 來源宿主
- 該Anti-Human Follistatin like-protein 1/FSTL1的詳細信息查看ReliaTech提供的產品說明書。
- 反應性
- 該Anti-Human Follistatin like-protein 1/FSTL1的詳細信息查看ReliaTech提供的產品說明書。
- 保存建議
- 該Anti-Human Follistatin like-protein 1/FSTL1的詳細信息查看ReliaTech提供的產品說明書。溶解建議：Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
- 其他
- ReliaTech全稱為受體配體技術有限公司 (Receptor Ligand Technologies GmbH)，1999年成立，總部位于德國不倫瑞克，是一家后基因組生物技術公司。ReliaTech主要專注于受體和配體的發(fā)現(xiàn)與研究。此外，ReliaTech也開發(fā)應用于血管與淋巴管生成研究的相關高品質試劑。目前ReliaTech提供近2800款產品，產品線主要包括重組蛋白(細胞因子、生長因子、可溶性受體)、抗體、ELISA試劑盒等。
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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