GDNF family receptor alpha-1 is a protein that in humans is encoded by the GFRA1 gene. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
應(yīng)用類型
WB
免疫原
該Anti-Human GDNF R alpha 3的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
來源宿主
該Anti-Human GDNF R alpha 3的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
反應(yīng)性
該Anti-Human GDNF R alpha 3的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
保存建議
該Anti-Human GDNF R alpha 3的詳細信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.