The synuclein family (SNCA) includes synuclein-alpha, -beta, and -gamma, and synoretin. These small, highly conserved proteins are localized predominantly in the brain, concentrated in presynaptic nerve terminals. Synuclein-alpha is normally a soluble protein. Abnormal synuclein-alpha forms filamentous inclusions (Lewy bodies and Lewy neurites) in several neurodegenerative diseases, including Parkinson's disease (PD), dementia with Lewy bodies, and Alzheimer's disease. Synucleins beta and gamma (synoretin) associate with synuclein-alpha and inhibit its aggregation.
應用類型
WB
免疫原
該Anti-Human SNCA的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
來源宿主
該Anti-Human SNCA的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
反應性
該Anti-Human SNCA的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
保存建議
該Anti-Human SNCA的詳細信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.