Transmembrane Protein with EGF-like and two Follistatin-like domains 1 (TMEFF1) also known as tomoregulin-1 is a type I transmembrane glycoprotein. TMEFF1 contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain of TMEFF1 can be released as a soluble protein. TMEFF1 is predominantly expressed in brain, but is downregulated in brain neoplasms. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto.
應(yīng)用類型
WB
免疫原
該Anti-Human TMEFF1的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
來源宿主
該Anti-Human TMEFF1的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
反應(yīng)性
該Anti-Human TMEFF1的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
保存建議
該Anti-Human TMEFF1的詳細信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.