Human TFPI is a physiological inhibitor of the extrinsic pathway of coagulation and functions in anticoagulation and anti-inflammation. It is a secreted protein with an N-terminal acidic region, three Kunitz (K) domains separated by two linker regions, and a C-terminal basic region. The first K domain inhibits coagulation factor VIIa complexed to tissue factor (TF). The second K domain inhibits factor Xa. The third K domain binds to heparin. The C-terminal basic region may have several functions. Human TFPI-2 is structurally similar to TFPI and is downregulated in several cancers.
該Anti-Human TFPI-2的詳細(xì)信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.