中文名稱

15-deoxy-Δ12,14-Prostaglandin J2-biotin (1 mg)

英文名字

15-deoxy-

供應商

Cayman

產(chǎn)品貨號

10141-1

產(chǎn)品報價

￥18816/1 mg

產(chǎn)品說明書

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產(chǎn)品新聞

背景資料

15-deoxy-.DELTA.12,14-Prostaglandin J2 -15-deoxy-.DELTA.12,14-PGJ2) is one of the cyclopentenone PGs, which have documented metabolic -peroxisome proliferator-activated receptor .gamma.-activating), antimitotic, and antiproliferative effects. The activity of the compounds in this class, which includes PGs in both the A- and J-series, may result from changes in gene expression and the interaction with non-classical -i.e., non-G protein-coupled receptor) pathways. 15-deoxy-.DELTA.12,14-PGJ2-biotin is an affinity probe which allows 15-deoxy-.DELTA.12,14-PGJ2 to be detected through an interaction with the biotin ligand. 15-deoxy-.DELTA.12,14-PGJ2-biotin was designed to allow 15-deoxy-.DELTA.12,14-PGJ2 to be detected in complexes with nuclear receptors and/or nucleic acid or protein binding partners. It is thus a tool to be used in the general elucidation of the mechanism of action of the cyclopentenone PGs.

產(chǎn)品描述

15-deoxy-.DELTA.12,14-Prostaglandin J2 -15-deoxy-.DELTA.12,14-PGJ2) is one of the cyclopentenone PGs, which have documented metabolic -peroxisome proliferator-activated receptor .gamma.-activating), antimitotic, and antiproliferative effects.{410,1349,13037} The activity of the compounds in this class, which includes PGs in both the A- and J-series, may result from changes in gene expression and the interaction with non-classical -i.e., non-G protein-coupled receptor) pathways. 15-deoxy-.DELTA.12,14-PGJ2-biotin is an affinity probe which allows 15-deoxy-.DELTA.12,14-PGJ2 to be detected through an interaction with the biotin ligand. 15-deoxy-.DELTA.12,14-PGJ2-biotin was designed to allow 15-deoxy-.DELTA.12,14-PGJ2 to be detected in complexes with nuclear receptors and/or nucleic acid or protein binding partners. It is thus a tool to be used in the general elucidation of the mechanism of action of the cyclopentenone PGs.

產(chǎn)品形式

保存建議

-20

其他

Cayman Chemical

注意

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