IL-4 can signal through type I and type II receptor complexes, which share a common gamma chain (γc).? The type I receptor contains, in addition to the γc, an IL-4Rα subunit, whereas the type II receptor contains the IL-13Rα.? The secreted extracellular domain of IL-4Rα, called sIL-4Rα, binds IL-4 and antagonizes its activity.? It plays an important role in regulating the differentiation of na?ve CD4+ T cells and class switching to IgG1 and IgE.?
該Anti-Human IL-4 receptor alpha, soluble的詳細(xì)信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.