Midkine (MK) and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis. Recombinant human Midkine is a 13.4 kDa protein containing 123 amino acid residues including five intra-molecular disulfide bonds.
應用類型
ELISA, WB
免疫原
該Anti-Human Midkine的詳細信息查看ReliaTech提供的產品說明書。
來源宿主
Rabbit
反應性
該Anti-Human Midkine的詳細信息查看ReliaTech提供的產品說明書。
保存建議
該Anti-Human Midkine的詳細信息查看ReliaTech提供的產品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.