HCC-1 or CCL14 is a chemokine that promotes chemotaxis of T cells, monocytes, and eosinophils. It occurs in two isoforms resulting from differential mRNA splicing. Following cleavage of a 19 amino acid signal peptide, mature CCL14a (aa 20-93) is a 74 amino acid peptide that is also known as HCC1 (Hemofiltrate CC Chemokine1). It is a weak CCR1 agonist, however, an 8 amino acid N-terminal truncation (aa 28-93) allows potent signaling through CCR1 and CCR5. CCL14b, also known as HCC3, is a 90 amino acid peptide (aa 20-109) resulting from the insertion of 16 amino acids between residues 7 and 8 of CCL14a.
應用類型
ELISA, WB
免疫原
該Anti-Human HCC-1的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
來源宿主
Rabbit
反應性
該Anti-Human HCC-1的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
保存建議
該Anti-Human HCC-1的詳細信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.