TL1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNF superfamily member 15 (TNFSF15). TL1A is predominantly expressed in endothelial cells and its expression is inducible by TNF-alpha and IL-1alpha. TL1A binds with high affinity to death receptor 3 (DR3), now known as TNFRSF25. Depending on the cell context, ligation of DR3 by TL1A can trigger one of two signaling pathways, activation of the transcription factor NF-kB, or activation of caspases and apoptosis.
該Anti-Human TL-1A的詳細(xì)信息查看ReliaTech提供的產(chǎn)品說(shuō)明書(shū)。溶解建議:Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.