IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.
應(yīng)用類型
ELISA, WB, N
免疫原
該Anti-Human IL-6的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
來源宿主
Rabbit
反應(yīng)性
該Anti-Human IL-6的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
保存建議
該Anti-Human IL-6的詳細信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.