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中文名稱

Anti-Mouse Ephrin-B1

英文名字
Anti-Mouse Ephrin-B1
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ReliaTech
產(chǎn)品貨號
103-M378
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¥詢價(jià)/100ug
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產(chǎn)品新聞
背景資料
EphrinB1, also known as LERK2, ELKL, EFL3, Cek5L, and STRA1, is a member of the ephrin ligand family which binds members of the Eph receptor family. All ligands share a conserved extracellular sequence, which most likely corresponds to the receptor binding domain. This conserved sequence consists of approximately 125 amino acids and includes four invariant cysteines. The Bclass ligands are transmembrane proteins which can become tyrosine phosphorylated upon receptor ligation. The cytoplasmic domains are approximately 80 amino acids long and are highly conserved, especially the last 33 amino acids. Several signaling molecules have been shown to interact with the cytoplasmic region, although specific signaling roles have yet to be elucidated. EphrinB1 has been shown to bind EphA3, EphB1, EphB2, EphB3, and EphB4. The extracellular domains of human and mouse EphrinB1 share 94% amino acid identity. Only membranebound or Fc-clustered ligands are capable of activating the receptor in vitro. Soluble monomeric ligands bind the receptor but do not induce receptor autophosphorylation and activation. In vivo, the ligands and receptors display reciprocal expression. It has been found that nearly all receptors and ligands are expressed in developing and adult neural tissue. The Eph/ephrin families also appear to play a role in angiogenesis.
應(yīng)用類型
WB
免疫原
該Anti-Mouse Ephrin-B1的詳細(xì)信息查看ReliaTech提供的產(chǎn)品說明書。
來源宿主
該Anti-Mouse Ephrin-B1的詳細(xì)信息查看ReliaTech提供的產(chǎn)品說明書。
反應(yīng)性
該Anti-Mouse Ephrin-B1的詳細(xì)信息查看ReliaTech提供的產(chǎn)品說明書。
保存建議
該Anti-Mouse Ephrin-B1的詳細(xì)信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.
其他
ReliaTech全稱為受體配體技術(shù)有限公司 (Receptor Ligand Technologies GmbH),1999年成立,總部位于德國不倫瑞克,是一家后基因組生物技術(shù)公司。ReliaTech主要專注于受體和配體的發(fā)現(xiàn)與研究。此外,ReliaTech也開發(fā)應(yīng)用于血管與淋巴管生成研究的相關(guān)高品質(zhì)試劑。目前ReliaTech提供近2800款產(chǎn)品,產(chǎn)品線主要包括重組蛋白(細(xì)胞因子、生長因子、可溶性受體)、抗體、ELISA試劑盒等。
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