GFR alpha -1, -2, -3, and -4 are GPI-anchored receptors that interact preferentially with the GDNF family ligands GDNF, Neurturin, Artemin, and Persephin, respectively. GFR alpha proteins initiate signaling in association with the receptor tyrosine kinase RET and by RET-independent pathways. GFR alpha-mediated signaling is instrumental in the differentiation, migration, and support of central and peripheral neurons. Alternative splicing generates multiple isoforms of GFR alpha proteins.
應用類型
ELISA, IHC (F)
免疫原
該Anti-Mouse GFR 4 alpha的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
來源宿主
該Anti-Mouse GFR 4 alpha的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
反應性
該Anti-Mouse GFR 4 alpha的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
保存建議
該Anti-Mouse GFR 4 alpha的詳細信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.