PARP, is a component of a base excision repair (BER) complex, containing at least XRCC1, PARP2, POLB and LRIG3. Widely expressed. Expression is correlated with proliferation, with higher levels occurring during early fetal development and organogenesis and in the highly proliferative cell compartments of adult. Expressed in Bcells that have been induced to switch to various Ig isotypes. PARP interacts with the DNA polymerase alpha catalytic subunit POLA1? this interaction functions as part of the control of replication fork progression.
應(yīng)用類型
WB
免疫原
該Anti-Mouse PARP的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
來源宿主
該Anti-Mouse PARP的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
反應(yīng)性
該Anti-Mouse PARP的詳細信息查看ReliaTech提供的產(chǎn)品說明書。
保存建議
該Anti-Mouse PARP的詳細信息查看ReliaTech提供的產(chǎn)品說明書。溶解建議:Centrifuge vial prior to opening. Reconstitute the antibody with 500 μl sterile PBS and the final concentration is 200 μg/ml.