Protein farnesylation is a posttranslational modification where a farnesyl isoprenoid moiety is attached to cysteine residues located near the C-terminus of proteins. Farnesyl alcohol azide acts as a replacement for endogenously-produced farnesyl alcohol and becomes attached to proteins through normal biological processes in cells or animals. The terminal azide group can then be used in simple chemical linking reactions, known as click chemistry , to readily tag farnesylated proteins for subsequent analysis.
產品描述
Acts as a replacement for endogenously-produced farnesyl alcohol and becomes attached to proteins through normal biological processes, in cells or animals; the terminal azide group can be used to readily tag farnesylated proteins via click chemistry for subsequent analysis