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中文名稱(chēng)

Cicaprost (10 mg)

英文名字
ZK 9648, Cicaprost, 2-[2-[(2E,3aS,4S,5R,6aS)-hexahydro-5-hydroxy-4-[(3S,4S)-3-hydroxy-4-methyl-1,6-nonadiyn-1-yl]-2(1H)-pentalenylidene]ethoxy]-acetic acid
供應(yīng)商
Cayman
產(chǎn)品貨號(hào)
16831-10
產(chǎn)品報(bào)價(jià)
¥35868/10 mg
產(chǎn)品說(shuō)明書(shū)
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產(chǎn)品新聞
背景資料
Prostaglandin I2 -PGI2, prostacyclin) is the most potent endogenous vasodilator that affects both the systemic and pulmonary circulation. Cicaprost is a PGI2 analog that is orally active with prolonged availability in vivo, having a terminal half life in plasma of one hour. In addition to their effects on smooth muscle, PGI2 analogs, including cicaprost, have been shown to inhibit the pro-inflammatory actions of certain leukocytes, suppress cardiac fibrosis, and block mitogenesis of certain cell types. Importantly, cicaprost has been shown to strongly reduce lung and lymph node metastasis in rats, suggesting that it might be useful in cancer therapy.
產(chǎn)品描述
A prostacyclin analog that is orally active with prolonged availability in vivo, having a terminal half-life in plasma of one hour; inhibits the pro-inflammatory actions of certain leukocytes, suppresses cardiac fibrosis, and blocks mitogenesis of certain cell types
產(chǎn)品形式
保存建議
-20
其他
Cayman Chemical
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