TACE Inhibitor, Screening BioAssay Kit (Tumor Necrosis Factor-alpha-converting Enzyme, ADAM Metallopeptidase Domain 17, ADAM17)-TACE Inhibitor, Screening BioAssay Kit (Tumor Necrosis Factor-alpha-converting Enzyme, ADAM Metallopeptidase Domain 17, ADAM17)代理/參數(shù)/廠家-細胞分析試劑盒-艾美捷科技有限公司

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中文名稱: TACE Inhibitor, Screening BioAssay Kit (Tumor Necrosis Factor-alpha-converting Enzyme, ADAM Metallopeptidase Domain 17, ADAM17)

英文名字: TACE Inhibitor, Screening BioAssay Kit (Tumor Necrosis Factor-alpha-converting Enzyme, ADAM Metallopeptidase Domain 17, ADAM17)

供應(yīng)商: USBiological

產(chǎn)品貨號: 169750

產(chǎn)品報價: ￥1/1Kit

產(chǎn)品說明書: 點擊查看

購買方式: 銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868

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產(chǎn)品描述: The TACE (tumor necrosis factor-alpha-converting enzyme), also called ADAM Metallopeptidase domain 17 (ADAM17), is a 70kD enzyme that belongs to the ADAM protein family of disintegrins and metalloproteases. TACE is believed to be involved in the processing of tumor necrosis factor alpha (TNF-alpha) at the surface of the cell, and from within the intracellular membranes of the trans-Golgi network. This process, which is also known as 'shedding', involves the cleavage and release of a soluble ectodomain from membrane-bound pro-proteins (such as pro-TNF-alpha), and is of known physiological importance.Intended Use:TACE hydrolyzes the specific FRET substrate to release the quenched fluorescent group, which can be detected fluorometrically at Ex/Em = 318/449nm.Specificity:MammalianTest Principle:In the presence of the potent TACE inhibitor, the hydrolyzation of substrate will be impeded. The kit provides a rapid, simple, sensitive and reliable test suitable for high-throughput screening of TACE inhibitors and can be modified to check the relative TACE activity. Inhibitor Control GM6001 is included to compare the efficacy of test inhibitors.Kit Components:Assay buffer, 1x25mlSubstrate, 1x0.2mlEnzyme (20ug), 1x1vialInhibitor Control, 1x20ulStorage and Stability:Store powder at 4°C, liquid at -20°C. Store other components at 4°C. Stable for at least 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

產(chǎn)品特點: 針對TACE Inhibitor, Screening BioAssay Kit (Tumor Necrosis Factor-alpha-converting Enzyme, ADAM Metallopeptidase Domain 17, ADAM17)該產(chǎn)品的特點優(yōu)勢，歡迎查閱官網(wǎng)提供的產(chǎn)品說明書。

保存建議: 建議收到TACE Inhibitor, Screening BioAssay Kit (Tumor Necrosis Factor-alpha-converting Enzyme, ADAM Metallopeptidase Domain 17, ADAM17)產(chǎn)品后將其置于-20°C保存。

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