SB 216763(1毫克)產(chǎn)品是A potent, cell-permeable and ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK-3) (Ki= 9 nM for GSK-3α). Has little activity against 24 other protein kinases (IC?? > 10 uM). Stimulates glycogen synthesis, gene transcription and is neuroprotective.