鈣蛋白酶抑制劑I,ALLN(25毫克)產(chǎn)品是A cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 0.5 nM). Inhibits neutral cysteine proteases and the proteasome (Ki = 6 uM). Can initiate apoptosis in HL-60 cells but blocks dexamethasone-induced apoptosis in thymocytes and cycloheximide-induced apoptosis in metamyelocytes. Inhibits cyclin B degradation and arrests the cell cycle at G1/S and at meta-/anaphase.
產(chǎn)品形式
艾美捷科技為您提供的BioVision原裝進(jìn)口Calpain Inhibitor I, ALLN產(chǎn)品為白色固體粉末形式.