CDK5 antibody recognizes the neuronal protein kinase Cdk5 which is implicated in a vast array of normal neuronal functions including regulation of neurotransmitter synthesis, the presynaptic vesicle cycle, neurotransmitter receptor trafficking and dopamine neurotransmission. At the same time Cdk5 has been implicated in a plethora of neurological and neuropsychiatric disorders including Alzheimer’s, Parkinson’s, Huntington’s, epilepsy, schizophrenia, and drug addiction. Detection of Cdk5 in normal samples as well as tissue undergoing neurodegeneration may advance studies in these areas. Moreover, this antibody may allow more accurate postmortem evaluations of Cdk5 protein expression, and thus serve as a valuable new reagent for neuropathology. Anti-CDK5 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
應(yīng)用類型
Immunohistochemistry,Western Blot,
免疫原
Anti-CDK5 Antibody was produced by repeated immunizations with purified rat Cdk5
來源宿主
Mouse
反應(yīng)性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建議
Store vial at -20° C prior to opening.? This product is stable at 4° C as an undiluted liquid.? For extended storage, aliquot contents and freeze at -20° C or below.? Avoid cycles of freezing and thawing. Dilute only prior to immediate use.