- 中文名稱
【干冰】Anti-ABCA4 (Rim Protein) (Mouse) Monoclonal Antibody - 200-301-D05
- 英文名字
- 【干冰】Anti-ABCA4 (Rim Protein) (Mouse) Monoclonal Antibody - 200-301-D05
- 供應(yīng)商
- Rockland
- 產(chǎn)品貨號
- 200-301-D05
- 產(chǎn)品報(bào)價(jià)
- ¥詢價(jià)/100uL

- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購買方式
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- 產(chǎn)品新聞

- 背景資料
- ABCA4 antibody detects ABCA4 (ATP-binding cassette, sub-family A (ABC1), member 4, Rim Protein) a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABCA4 is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essential molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease and are associated with retinitis pigmentosa-19 and age-related macular degeneration. Defects in ABCA4 are the cause of Stargardt disease type 1 (STGD1). STGD is one of the most frequent causes of macular degeneration in childhood. Defects in ABCA4 are also known to cause fundus flavimaculatus (FFM), age-related macular degeneration type 2 (ARMD2) and cone-rod dystrophy type 3 (CORD3). Anti-ABCA4 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
- 應(yīng)用類型
- ELISA,Immunohistochemistry,Western Blot,
- 免疫原
- Anti-ABCA4 antibody was produced by repeated immunizations with 220-kDa (full length) partially purified native bovine disc rim protein.
- 來源宿主
- Mouse
- 反應(yīng)性
- Bovine (Bos Taurus); H. sapiens (Human); Mus musculus (Mouse); Xenopus
- 保存建議
- Store vial at -20° C prior to opening.? This product is stable at 4° C as an undiluted liquid.? For extended storage, aliquot contents and freeze at -20° C or below.? Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
- 其他
- Rockland成立于1962年,是一家老牌抗體原產(chǎn)企業(yè),其位于美國費(fèi)城郊區(qū)的農(nóng)場保有近20種實(shí)驗(yàn)動物。Rockland公司為生命科學(xué)領(lǐng)域提供豐富的、高質(zhì)量的抗體,包括載脂蛋白、細(xì)胞周期/凋亡、細(xì)胞因子、細(xì)胞信號蛋白、酶類、細(xì)胞外基質(zhì)、轉(zhuǎn)錄因子(NFkB)和泛素(Ubiquitin)等識別抗體,應(yīng)用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外,Rockland也生產(chǎn)特別齊全的二抗,包括純化、生物素、HRP/ALP、熒光標(biāo)記二抗,應(yīng)用十分廣泛。

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