Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulartion by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway. TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure.
TrpC7 Antibody was produced in mice by repeated immunizations raised against a synthetic peptide corresponding to a near c-terminus region of human TrpC7.
來源宿主
Mouse
反應性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建議
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