MEK2 antibodies detect the MEK2 isoform. ?Mitogen-activated protein kinase kinase 2, also known as MEK2 or MKK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ? This pathway also plays a key role in synaptic plasticity in the brain. ?Activated MEK 2 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. ? MEK1 and MEK2 are about 80% identical to each other, and nearly identical within the kinase domain. ?This antibody does not react with MEK1. ?The MEK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.
應用類型
ELISA,Western Blot,
免疫原
Anti-MEK2 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the C-terminus conjugated to KLH.
來源宿主
Mouse
反應性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建議
Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.