Anti-CD4 (MOUSE) Fluorescein Conjugated Monoclonal Antibody - 200-302-N18-Anti-CD4 (MOUSE) Fluorescein Conjugated Monoclonal Antibody

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中文名稱: Anti-CD4 (MOUSE) Fluorescein Conjugated Monoclonal Antibody - 200-302-N18

英文名字: Anti-CD4 (MOUSE) Fluorescein Conjugated Monoclonal Antibody - 200-302-N18

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背景資料: The OKT4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.The OKT4 antibody is widely used as a phenotypic marker for CD4 expression.

應(yīng)用類型: Flow Cytometry,Immunohistochemistry,IF Microscopy,Immunoprecipitation,Western Blot,

免疫原: Anti-CD4 Antibody (Monoclonal) was produced by repeated immunizations with CD4 antigen.

保存建議: Store vial at 4° C prior to opening.? This product is stable for several weeks at 4° C as an undiluted liquid.? Dilute only prior to immediate use.? DO NOT FREEZE. This product is light sensitive.

其他: Rockland成立于1962年，是一家老牌抗體原產(chǎn)企業(yè)，其位于美國費城郊區(qū)的農(nóng)場保有近20種實驗動物。Rockland公司為生命科學(xué)領(lǐng)域提供豐富的、高質(zhì)量的抗體，包括載脂蛋白、細(xì)胞周期/凋亡、細(xì)胞因子、細(xì)胞信號蛋白、酶類、細(xì)胞外基質(zhì)、轉(zhuǎn)錄因子(NFkB)和泛素（Ubiquitin）等識別抗體，應(yīng)用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產(chǎn)特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標(biāo)記二抗，應(yīng)用十分廣泛。