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中文名稱

Anti-CD45 (MOUSE) Phycoerythrin Conjugated Monoclonal Antibody - 200-308-N68

英文名字
Anti-CD45 (MOUSE) Phycoerythrin Conjugated Monoclonal Antibody - 200-308-N68
供應(yīng)商
Rockland
產(chǎn)品貨號(hào)
200-308-N68
產(chǎn)品報(bào)價(jià)
￥詢價(jià)/500uL
產(chǎn)品說(shuō)明書(shū)
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產(chǎn)品新聞
背景資料
CD45 is a 180-240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
應(yīng)用類(lèi)型
Flow Cytometry,Immunohistochemistry,Western Blot,
免疫原
Anti-CD45 Antibody (Monoclonal) was produced by repeated immunizations with CD45 antigen.
來(lái)源宿主
Mouse
反應(yīng)性
H. sapiens (Human)
保存建議
Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
其他
Rockland成立于1962年，是一家老牌抗體原產(chǎn)企業(yè)，其位于美國(guó)費(fèi)城郊區(qū)的農(nóng)場(chǎng)保有近20種實(shí)驗(yàn)動(dòng)物。Rockland公司為生命科學(xué)領(lǐng)域提供豐富的、高質(zhì)量的抗體，包括載脂蛋白、細(xì)胞周期/凋亡、細(xì)胞因子、細(xì)胞信號(hào)蛋白、酶類(lèi)、細(xì)胞外基質(zhì)、轉(zhuǎn)錄因子(NFkB)和泛素（Ubiquitin）等識(shí)別抗體，應(yīng)用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外，Rockland也生產(chǎn)特別齊全的二抗，包括純化、生物素、HRP/ALP、熒光標(biāo)記二抗，應(yīng)用十分廣泛。
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