Anti-CD62L antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte rolling on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
Anti-CD62L Antibody (Monoclonal) was produced by repeated immunizations with CD62L antigen.
來(lái)源宿主
Rat
反應(yīng)性
Mus musculus (Mouse)
保存建議
Store vial at 4° C prior to opening.? This product is stable for several weeks at 4° C as an undiluted liquid.? Dilute only prior to immediate use.? DO NOT FREEZE. This product is light sensitive.