- 中文名稱
Anti-CD45R (B220) (RAT) Phycoerythrin Conjugated Monoclonal Antibody - 200-508-N84
- 英文名字
- Anti-CD45R (B220) (RAT) Phycoerythrin Conjugated Monoclonal Antibody - 200-508-N84
- 供應(yīng)商
- Rockland
- 產(chǎn)品貨號(hào)
- 200-508-N84
- 產(chǎn)品報(bào)價(jià)
- ¥詢價(jià)/200ug

- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購買方式
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- 產(chǎn)品新聞

- 背景資料
- CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
- 應(yīng)用類型
- Flow Cytometry,Immunohistochemistry,Immunoprecipitation,
- 免疫原
- Anti-CD45R (B220) Antibody (Monoclonal) was produced by repeated immunizations with Abelson murine leukemia virus-induced pre-B tumor cells.
- 來源宿主
- Rat
- 反應(yīng)性
- H. sapiens (Human); Mus musculus (Mouse)
- 保存建議
- Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
- 其他
- Rockland成立于1962年,是一家老牌抗體原產(chǎn)企業(yè),其位于美國費(fèi)城郊區(qū)的農(nóng)場保有近20種實(shí)驗(yàn)動(dòng)物。Rockland公司為生命科學(xué)領(lǐng)域提供豐富的、高質(zhì)量的抗體,包括載脂蛋白、細(xì)胞周期/凋亡、細(xì)胞因子、細(xì)胞信號(hào)蛋白、酶類、細(xì)胞外基質(zhì)、轉(zhuǎn)錄因子(NFkB)和泛素(Ubiquitin)等識(shí)別抗體,應(yīng)用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外,Rockland也生產(chǎn)特別齊全的二抗,包括純化、生物素、HRP/ALP、熒光標(biāo)記二抗,應(yīng)用十分廣泛。

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