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中文名稱

Hemopexin, Rat

英文名字
Hemopexin, Rat
供應(yīng)商
USBiological
產(chǎn)品貨號
208953
產(chǎn)品報價
¥1/25ug
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產(chǎn)品新聞
背景資料
USBiological品牌是全球有名的抗原抗體和生化試劑供應(yīng)商,生產(chǎn)世界上種類最多的抗體,用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細(xì)胞術(shù)等多種檢測方法。武漢艾美捷科技作為USBiological品牌中國區(qū)域總代理,是行業(yè)中少有的致力于服務(wù)客戶,幫助客戶,且擁有獨立的專業(yè)銷售團(tuán)隊、技術(shù)支持團(tuán)隊、市場營銷團(tuán)隊、進(jìn)出口報關(guān)團(tuán)隊的高科技生物企業(yè)。可以為您提供及時的咨詢響應(yīng),專業(yè)的產(chǎn)品和解決方案支持,穩(wěn)健快捷的交貨周期,優(yōu)質(zhì)放心的售后服務(wù)。我們致力于為您提供有價值的產(chǎn)品和服務(wù),在意您的成功!
產(chǎn)品描述
Hemopexin, a globulin (beta-glycoprotein) synthesized by liver, accounts for about 1.4% of total serum protein. Like albumin, it binds heme with high affinity and transports it to liver for salvage of the iron. Human hemopexin consists of a single polypeptide chain of 439 amino acids (~50-57kD, carbohydrate ~23%; plasma concn in human 0.8-1 mg/ml). Structurally hemopexin consists of two similar halves of ~two hundred amino acid residues connected by a histidine rich hinge region. Each half is itself formed by the repetition of a basic unit of some 35 to 45 residues. Hemopexin has been found in the serum of all mammals studied and it is polymorphic in rabbits and swine. Hemopexin is an acute phase protein that is elevated 2-3 fold in rat serum and plasma as a result of inflammation and arthritis. Hemopexin provides a convenient marker of inflammation and tissue injury in the rat.Recent studies have demonstrated that hemopexin acts as an extracellular antioxidant against hemoglobin- mediated damage in inflammation. Hemopexin protects against heme toxicity and conserves and recycles iron. Abnormal levels of hemopexin are associated with hemolytic anemia, chronic neuromuscular disease, and acute intermittent porphyria.Source:Hemopexin, from a pool of rat serumApplications: Suitable for use in ELISA and Western Blot. Other applications not tested.Recommended Dilution:ELISA: 0.1-1ug/mlWestern Blot: load 100-500ng/lane and probe with antibodiesOptimal dilutions to be determined by the researcher.Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
產(chǎn)品形式
該產(chǎn)品為液體形式,緩沖液為:10mM sodium phosphate, pH 7.2, 150mM sodium chloride, 0.05% sodium azide。
保存建議
接收到Hemopexin, Rat產(chǎn)品后,置于-20°C溫度下保存。
其他
Usbiological公司是美國著名的抗體和生化試劑供應(yīng)商,生產(chǎn)世界上種類最多的抗體,用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細(xì)胞術(shù)等多種檢測方法。Usbiological公司現(xiàn)已擁有超過50,19234種抗體、抗原和生化產(chǎn)品,為科研用戶提供了諸多超值選擇。
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