NU6102(1毫克)產(chǎn)品是A potent inhibitor of CDK1 and CDK2 with Ki values of 9 and 6 nM and IC?? values of 9.5 and 5.4 nM, respectively. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC?? = 1.6 uM), DYRK1A (IC?? = 0.9 uM), PDK1 (IC?? = 0.8 uM) and ROCK-II (IC?? = 0.6 uM). Inhibits cell growth.