BMS-911543(1毫克)產(chǎn)品是BMS-911543 is a potent and selective JAK2 inhib itor. It displays potent anti-proliferative and pharmacodynamic effects in cell lines dependent upon JAK2 signaling, and has little activity in cell types dependent upon other pathways, such as JAK1 and JAK3.?In addition, it?displays anti-proliferative responses in colony growth assays using primary progenitor cells isolated from patients with JAK2(V617F)-positive myeloproliferative neoplasms (MPNs).