MK-571(5毫克)產(chǎn)品是MK-571 is a selective, CysLT1?receptor antagonist. It blocks the binding of leukotriene LTD4, but not LTC4, to human and guinea pig lung membranes with Ki?values of 0.22 nM and 2.1 nM, respectively. MK 571 effectively blocks LTD4?activation of recombinant human and murine CysLT1?receptors?but is ineffective at blocking LTC4?or LTD4activation of the recombinant human or murine CysLT2?receptors. MK-57 also acts as a specific inhibitor of multi-drug resistance protein-1 (MRP1).