TW-37(5毫克)產(chǎn)品是TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 uM, 1.11 uM and 0.26 uM, respectively. ?TW-37 inhibits the growth of a broad range of cancer cells (such as breast, prostate, lymphoma, and pancreatic cancer), since it induces S-phase cell cycle arrest with regulation of several important cell cycle related genes, including?p27, p57, E2F-1, cdc25A, CDK4, cyclin A, cyclin D1 and cyclin E.